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12 Best Custom Skincare Brands That Work

Last Updated: November 17, 2022

The best custom skincare brands cater to your specific goals for clear skin. Keep reading to find our top picks!

The rising popularity of custom skincare products is undeniable, so it can be hard to narrow down which one will work the best.

Most brands offer their patients a short quiz that asks about lifestyle, skin type, or concern, or even asks for an in-depth skin analysis. Every brand is different in its approach to the customized formulations that they provide, but they all have the same goal: to give you your best skin yet. 

These custom skincare brands claim to be the resolution to skin concerns that will effectively treat their skincare problems at their root cause. 

We have thoroughly searched for brands and have created a list of the 12 best custom skincare brands to check out for clear, healthy skin. 

Best Custom Skincare Brands

📷 IG @clinique

Clinique ID

With Clinique ID, you’re able to choose between six different base formulas or moisturizers, and nine different active cartridge concentrations.

Each active concentration targets different areas of concern (such as redness, large pores, hyperpigmentation, dullness, fine lines, and many more).

There are over 30 combinations that their customers are able to select from their Clinique ID and it costs $41.

📷 IG @curology


Curology was co-founded by board-certified dermatologist David Lortscher with a mission to help treat acne.

This brand connects its patients with a dermatologist who will assess their selfies to determine the best treatment cream. They are also a pretty affordable option, offering treatment for $20-$30 a month.

There are numerous glowing reviews about Curology’s effectiveness, and you can receive your first formula for free.

RELATED: Our Honest Curology Review

📷 IG @iloveskininc

Skin Inc My Daily Dose

Skin Inc creates tailor-made skincare by utilizing technology from Japan to create their custom serum with three encapsulated boosters. 

These boosters contain different ingredients to treat skin concerns, something they call your “skincare cocktail.”

They assess your skin against over 1 million different skin profiles to provide a booster to be mixed with your custom serum. 

📷 IG @provenskincare


Proven was created as part of The Skin Genome Project at MIT in 2018 and received the Artificial Intelligence Award in collaboration with S. Tyler Hollmig, head of aesthetic dermatology at Stanford University.

After taking the quiz about your skin concerns, skin type, lifestyle, and environmental factors, Stanford dermatologists formulate a three-step skincare routine including a cleanser, day moisturizer, and night cream. This does come at a high price point, though. 

RELATED: Our PROVEN Skincare Reviews

📷 IG @functionofbeauty

Function of Beauty (Atolla)

Once known as Atolla, this customized skincare brand was recently acquired by Function of Beauty, the brand that became famous for its customized hair care.

At Function of Beauty, you’ll be asked about your skin type, concerns, and your skin goals to determine your personalized skincare regimen.

You then have the choice to make a one-time purchase to try your custom skincare, or you can subscribe and have it delivered every 3 months! 

📷 IG @skinceuticals

SkinCeuticals Custom D.O.S.E 

SkinCeuticals is already known for being a skincare brand recommended by dermatologists, and they are taking their skincare products to a new level.

They have created Customer D.O.S.E (Diagnostic Optimization Serum Experience), where customers and their participating dermatologists are able to create a customized serum in less than 10 minutes determined by a series of 85,000 algorithms.

📷 IG @vitruvi

Vitruvi Dynamic Skincare

This customized skincare brand offers a customized oil, created after taking a short quiz offered by Vitruvi. The oil contains a base, complex oil, and essential oil that will best serve your skin type.

The oils will arrive at your door individually packed and will have to be mixed in order to create the customized facial oil. 

📷 IG @younique_corporate

Younique YouOlogy

A complete skincare routine that includes a cleanser, serum, and day and night moisturizers after taking Younique’s online quiz.

There are over 40,000 possible combinations depending on customers’ answers. Younique also offers pre-formulated eye creams, exfoliants, and masks. 

📷 IG @skinsei.skincare

Skinsei Synergistic Skincare

After taking Skinsei’s seven-part diagnostic test that analyzes climate, sleep, exercise, and skin concerns, Skinsei creates a custom 3-5 product skincare regimen.

In addition, they offer the option to purchase a kit for a one-time purchase or save by signing up for a subscription. They offer affordable pricing which ranges from $45 to $65 a month.

📷 IG @kiehls

Kiehl’s Apothecary Preparations 

Available at select boutiques, a Kiehl’s representative will analyze customers’ skin and discuss skin goals and concerns to create a squalane-based concentrate with a choice of seven complexes. 

You can also have an online consultation with one of their expert skin consultants, or you can upload a selfie for them to analyze to recommend the best products for you. 

📷 IG @pureculturebeauty

Pure Culture Beauty 

This brand offers a personalized quiz that asks about the two main skincare concerns of their clients, followed by a series of questions about lifestyle, sleep, diet, and sun exposure

In addition, they also send a skin barrier test and a skin condition test to your home to determine hydration levels and the effect of daily environmental aggressors.

The custom skincare set includes a cleanser, serum, and moisturizer that retails for $100.

📷 IG @dermatica.skin


A simple questionnaire will begin in treating skin concerns from acne, anti-aging, pigmentation, or melasma. Dermatica’s dermatology team will determine the best evidence-based treatment for each patient.

They offer a monthly subscription starting at $25 a month, and they also offer support from their medical professionals.

In Conclusion 

These best custom skincare brands offer personalized regimens for your clearest skin. The brands above are some of the top-rated options out there and are a great place to start curating your custom skincare routine.

It might take some trial and error, but if there’s one thing we’ve learned, it’s that skincare isn’t one size fits all. One of these brands is bound to have the perfect solution for you. 

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